THE INDISCRIMINATE USE OF NAPHOZALINE FOR NASAL CONGESTION: A LITERATURE REVIEW

Authors

  • Denise Gonçalves Borges Centro Universitário da Amazônia
  • Evelyn Luna Nunes de Carvalho Centro Universitário da Amazônia
  • Luís Alberto Silva Santiago Centro Universitário da Amazônia
  • Gleicy Kelly China Quemel Universidade do Estado da Amazônia

DOI:

https://doi.org/10.51891/rease.v12i11.32066

Keywords:

Nasal decongestants, Imidazolinones, Rebound congestion, Pharmacist, Rational use of medicines

Abstract

The indiscriminate use of naphazoline is a public health concern, particularly due to the ease of access to the medication, the prevalence of self-medication, and its prolonged use without professional guidance. In this context, this study aimed to analyze the risks associated with the indiscriminate use of naphazoline for treating nasal congestion, highlighting the importance of pharmaceutical guidance for the rational use of this drug. The methodology employed was an integrative literature review, based on scientific publications available in the PubMed/MEDLINE, BVS, LILACS, and SciELO databases, covering the period from 2017 to 2026, and utilizing Bardin’s content analysis method. Fifteen studies were selected for analysis, which demonstrated that while naphazoline provides temporary relief from nasal obstruction through vasoconstriction, its inappropriate use can lead to rebound congestion and systemic adverse effects in cases of excessive exposure. Furthermore, the study found that self-medication, ease of access, and a lack of awareness regarding the associated risks contribute to improper usage, underscoring that pharmaceutical intervention is essential for promoting the safe and rational use of naphazoline.

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Author Biographies

  • Denise Gonçalves Borges, Centro Universitário da Amazônia

    Discente do curso de Bacharelado em Farmácia. Centro Universitário da Amazônia (UNIESAMAZ), Brasil. 

  • Evelyn Luna Nunes de Carvalho, Centro Universitário da Amazônia

    Discente do curso de Bacharelado em Farmácia. Centro Universitário da Amazônia (UNIESAMAZ), Brasil. 

  • Luís Alberto Silva Santiago, Centro Universitário da Amazônia

    Discente do curso de Bacharelado em Farmácia. Centro Universitário da Amazônia (UNIESAMAZ), Brasil. 

  • Gleicy Kelly China Quemel, Universidade do Estado da Amazônia

    Orientadora. Mestre em Ciências Ambientais pela Universidade do Estado da Amazônia. Graduada em Ciências Naturais com Habilitação em Química pela Universidade Federal do Pará. 

Published

2026-11-12

How to Cite

Borges, D. G., Carvalho, E. L. N. de, Santiago, L. A. S., & Quemel, G. K. C. (2026). THE INDISCRIMINATE USE OF NAPHOZALINE FOR NASAL CONGESTION: A LITERATURE REVIEW. Revista Ibero-Americana de Humanidades, Ciências E Educação, 12(11), 1-18. https://doi.org/10.51891/rease.v12i11.32066