TIME IS BRAIN: MULTIPROFESSIONAL CARE IN THE MANAGEMENT OF STROKE WITHIN THE THERAPEUTIC WINDOW

Authors

  • Elis Regina de Oliveira Ferreira Gran
  • Neidja Cristine Silvestre Leitão Anhembi
  • Alexsandro Barros Errico Faculdade IMES
  • Nayane Regina Silva Araújo Federal University of Uberlândia image/svg+xml
  • Lucas Antônio de Moraes Silva Faculdade Anhanguera image/svg+xml
  • Giullia Camila Bortoto UNICESUMAR
  • Beatriz Botacin Regino Catelan UNICESUMAR
  • Luciana Silva Gomes ZARNS
  • Jennfer Caroline Alves Fernandes ZARNS
  • Arquimedes Cavalcante Cardoso UFPI
  • Adriano Nogueira da Cruz UEMA-CESC
  • Edivaldo Bazilio dos Santos FacLions
  • Renata Sabino Tupinambá ZARNS
  • Gabriel Tanure Cordeiro ZARNS

DOI:

https://doi.org/10.51891/rease.v12i9.29616

Keywords:

Stroke. Thrombolytic Therapy. Patient Care Team. Emergency Nursing. Emergency Medical Services. Time-to-Treatment.

Abstract

Objective: To synthesize the best scientific evidence on multiprofessional team performance in the care of patients with acute ischemic stroke (AIS) within the therapeutic window, emphasizing strategies that reduce door-to-needle and door-to-puncture times and improve clinical outcomes. Method: Integrative review conducted according to Whittemore and Knafl and reported following PRISMA 2020, with searches in PubMed/MEDLINE, LILACS, SciELO and the Virtual Health Library, covering publications from 2020 to 2026. Controlled descriptors (DeCS/MeSH) combined with Boolean operators were used. Methodological quality and level of evidence were assessed according to Melnyk and Fineout-Overholt. Results: 24 studies were included. Evidence converges on the consistent effect of coordinated action by nurses, physicians, nursing technicians, pharmacists, radiologists, physiotherapists, speech-language pathologists, nutritionists and psychologists on process and outcome indicators. Nurse-led interventions reduced door-to-needle time by 16 to 20 minutes on average and increased thrombolysis rates; prehospital notification and the Stroke Code shortened door-to-CT and door-to-needle times; early dysphagia screening reduced aspiration pneumonia and mortality. Final considerations: Structured multiprofessional care, supported by protocols, effective communication, simulation and continuing education, is a modifiable determinant of AIS outcomes within the therapeutic window, with direct implications for nursing practice, hospital management and public policies of the emergency care network.

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Author Biographies

  • Elis Regina de Oliveira Ferreira, Gran

    Pós-graduação em Saúde pública com Ênfase em Vigilância Sanitária, Gran Centro Universitário.

  • Neidja Cristine Silvestre Leitão, Anhembi

    Graduanda Medicina, Anhembi Morumbi.

  • Alexsandro Barros Errico, Faculdade IMES

    Pós-graduação em Análise do Comportamento aplicada ao autismo -ABA-, Faculdade IMES.

  • Nayane Regina Silva Araújo, Federal University of Uberlândia

    Mestrado em Saúde Ambiental e Saúde do Trabalhador UFU, Universidade Federal de Uberlândia.

  • Lucas Antônio de Moraes Silva, Faculdade Anhanguera

    Pós-graduação em Urgência e Emergência, Faculdade Anhanguera.

  • Giullia Camila Bortoto, UNICESUMAR

    Graduanda em Medicina, UNICESUMAR.

  • Beatriz Botacin Regino Catelan, UNICESUMAR

    Graduanda em Medicina, UNICESUMAR.

  • Luciana Silva Gomes, ZARNS

    Graduanda em Medicina, ZARNS. 

  • Jennfer Caroline Alves Fernandes, ZARNS

    Graduanda em Medicina, ZARNS.

  • Arquimedes Cavalcante Cardoso, UFPI

    Mestrado em Ciências e Saúde, Centro de Ciências da Saúde/UFPI.

  • Adriano Nogueira da Cruz, UEMA-CESC

    Graduado em Enfermagem, UEMA-CESC.

  • Edivaldo Bazilio dos Santos, FacLions

    Pós-graduação em terapia intensiva, FacLions.

  • Renata Sabino Tupinambá, ZARNS

    Graduanda em Medicina, ZARNS.

  • Gabriel Tanure Cordeiro, ZARNS

    Graduando em Medicina, ZARNS.

Published

2026-09-04

How to Cite

Ferreira, E. R. de O., Leitão, N. C. S., Errico, A. B., Araújo, N. R. S., Silva, L. A. de M., Bortoto, G. C., Catelan, B. B. R., Gomes, L. S., Fernandes, J. C. A., Cardoso, A. C., Cruz, A. N. da, Santos, E. B. dos, Tupinambá, R. S., & Cordeiro, G. T. (2026). TIME IS BRAIN: MULTIPROFESSIONAL CARE IN THE MANAGEMENT OF STROKE WITHIN THE THERAPEUTIC WINDOW. Revista Ibero-Americana de Humanidades, Ciências E Educação, 12(9), 1-22. https://doi.org/10.51891/rease.v12i9.29616

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