HEART FAILURE IN PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS: CLINICAL TREATMENT AND CARDIOVASCULAR IMPERCUSSIONS

Abstract

Introduction: Heart failure (HF) is a significant complication in patients with systemic lupus erythematosus (SLE), an autoimmune disease that affects multiple body systems. Studies have shown that chronic inflammation associated with SLE contributes to increased cardiovascular risk, leading to structural and functional changes in the heart. These changes can result in HF, which is characterized by the inability of the heart to pump blood effectively. Understanding the cardiovascular repercussions of SLE and the clinical treatment of HF in this context is essential to improve patient outcomes. Objective: To analyze the existing literature on heart failure in patients with systemic lupus erythematosus, focusing on clinical treatment and cardiovascular repercussions. Methodology: The methodology followed the PRISMA checklist guidelines, using databases such as PubMed, SciELO and Web of Science. Five descriptors were used: "systemic lupus erythematosus", "heart failure", "clinical treatment", "cardiovascular repercussions" and "cardiovascular health". Inclusion criteria included studies published in the last 10 years, articles in English and Portuguese, and those that explicitly addressed the relationship between SLE and HF. Exclusion criteria were studies that did not address heart failure, non-systematic reviews, and articles with duplicate data. Results: The review identified that HF ​​is one of the most serious complications of SLE, often related to disease activity and the use of medications, such as corticosteroids. The research also revealed that the treatment of HF in patients with SLE requires a multidisciplinary approach, involving both pharmacological therapies and non-pharmacological interventions. In addition, careful monitoring of cardiac function is essential to prevent complications. Conclusion: Heart failure in patients with systemic lupus erythematosus represents a significant challenge that requires specialized care. The integration of appropriate treatments and constant surveillance can improve the quality of life of these patients. Understanding the interactions between SLE and cardiovascular health is crucial for the development of more effective management strategies.