USE OF NANOTECHNOLOGY TO OPTIMIZE DRUG BIOAVAILABILITY

Abstract

Introduction: Nanotechnology has emerged as one of the most significant pharmaceutical innovations, particularly in improving drug delivery systems capable of enhancing the bioavailability and therapeutic efficacy of medications. The use of nanoparticles, nanocarriers, and nanostructured systems enables the optimization of absorption, distribution, and controlled release of active compounds in the body, minimizing side effects and increasing treatment specificity. Objectives: In this context, several studies have demonstrated the effectiveness of nanotechnology as an innovative strategy for optimizing pharmacological treatments, contributing to improved therapeutic efficacy and drug bioavailability without relying on conventional approaches. Therefore, this study aims to examine how nanotechnology contributes to improving drug bioavailability, highlighting its main mechanisms of action, therapeutic applications, and benefits in the pharmaceutical field. Methodology: This is a qualitative, descriptive, and exploratory study developed through a literature review of scientific databases such as BVS, SciELO, and PubMed, using descriptors related to pharmaceutical nanotechnology and drug delivery systems. Results: The findings indicate that nanotechnological systems have great potential to enhance the therapeutic efficacy of drugs by providing greater stability, controlled release, and targeted delivery of the drug to specific tissues. Conclusion: It is concluded that nanotechnology represents a promising strategy for the development of more effective and safer therapies, significantly contributing to the advancement of pharmacology and the improvement of the quality of drug treatments.