FACTORS ASSOCIATED WITH ADHERENCE AND NON-ADHERENCE TO PRE-EXPOSURE PROPHYLAXIS (PREP) AND THE ROLE OF NURSING IN HIV PREVENTION: A LITERATURE REVIEW

Abstract

Introduction: Pre-exposure prophylaxis (PrEP) for HIV is an important prevention strategy, and adherence is influenced by individual, social, and structural factors. In this context, understanding these factors is fundamental for improving nursing actions and strengthening HIV prevention strategies. Objective: To analyze the factors that interfere with adherence and non-adherence to PrEP, as well as the role of nurses in HIV prevention. Methodology: This is a literature review based on the analysis of scientific studies selected from the LILACS, SciELO, BVS, and PubMed databases. The following descriptors were used: Pre-Exposure Prophylaxis, HIV, Nursing, Prevention, and Treatment Adherence. Analysis and discussion of results: The results show that adherence to PrEP is related to the level of knowledge, access to information, and availability of different therapeutic regimens, such as daily use, on-demand regimen, and injectable PrEP. On the other hand, barriers such as social stigma, lack of information, adverse effects, forgetfulness regarding use, and difficulties in accessing health services stand out. Inequality of access is also observed among vulnerable populations, such as transgender people. In this scenario, the nurse's role is essential in health education and in strengthening the bond with the user.