HODGKIN LYMPHOMA IN BRAZIL: ANALYSIS OF AGE GROUP DISTRIBUTION AND HOSPITAL OUTCOMES

Abstract

Introduction: Hodgkin lymphoma is a hematologic malignancy characterized by a peculiar age distribution, significant hospital burden, and clinical course influenced by age. Although it often presents high cure rates, age-related differences may affect patterns of hospitalization, deaths, and in-hospital mortality. Objective: To analyze the epidemiological profile of Hodgkin lymphoma in Brazil by age group from 2016 to 2025. Methods: This was an epidemiological, observational, retrospective, descriptive, and quantitative study based on secondary data obtained from the Hospital Information System of the Brazilian Unified Health System (SIH/SUS), available through DATASUS. Hospitalizations, in-hospital deaths, and mortality rates were analyzed according to age group. Results: A total of 52,432 hospitalizations and 1,945 deaths due to Hodgkin lymphoma were recorded during the study period. The highest frequencies of hospitalization were observed among individuals aged 20 to 29 years and 10 to 19 years, whereas the highest in-hospital mortality rates were found in older age groups, especially those aged 70 to 79 years and 80 years or older. The lowest mortality rate was identified in the 10 to 19-year age group. Conclusion: Hodgkin lymphoma in Brazil showed a higher hospitalization burden among adolescents and young adults, but greater in-hospital lethality among older adults. These findings highlight the importance of age stratification for healthcare planning and for improving diagnostic and management strategies within the public health system.