USE OF DENTAL PULP STEM CELLS IN BONE REGENERATION

Abstract

Dental pulp stem cells can be stimulated or programmed to perform specific biological functions. Thus, they are important indications in the treatment of many diseases or in regenerative processes. The objective of the study was to conduct a literature review in order to discuss the evidence for the use of dental pulp stem cells in bone regeneration. For this, a literature review was performed through searches for scientific articles in the Scopus, Web of Science and Scielo databases. Studies published in the last five years (2020 to 2024) were collected, using the following descriptors: “Stem cells”, “Dental pulp” and “Bone regeneration”. The search in the databases resulted in 26 studies and after a thorough analysis, ten studies were selected and included in the present research. The literature review demonstrated favorable results regarding the evidence for the use of dental pulp stem cells for bone regeneration. Furthermore, advances in studies involving the subject may constitute a promising tool, since CTPDs are abundant and the procedure involving them presents a simple method of obtaining them and can be collected without injuring the donor or invasive surgical procedures.