LABORATORY INTERFERENCES CAUSED BY CAPTOPRIL

Abstract

This text addresses arterial hypertension (AH) as a global public health concern, highlighting its association with cardiovascular diseases and its significant mortality, including stroke and myocardial infarction. AH affects more than 1 billion people globally, being responsible for around 400 deaths annually in Brazil. The renin-angiotensin-aldosterone system (RAAS) plays a crucial role in regulating blood pressure, and medications such as captopril, an ACE inhibitor, are important for its treatment. This is an integrative bibliographic review of the literature, covering articles published between 1981 and 2018, focusing on the last 10 years. The bibliographic research was conducted using academic databases such as SciELO (Scientific Electronic Library Online) and BDENF (specialized bibliographic database in the area of Nursing), with selection criteria focused on articles in Portuguese related to the effects of anti-inflammatory drugs. hypertensive in laboratory results. In addition to the hematological changes associated with captopril, potential adverse effects were discussed, such as false-positive results in urine ketone tests and changes in biochemical parameters. Awareness of these issues and the integration of measures to identify and prevent drug interference are essential to promote accurate interpretation of laboratory tests and effective healthcare.