RELATIONSHIP BETWEEN PSORIASIS, DEPRESSION AND ANXIETY

Abstract

Psoriasis is a chronic inflammatory skin disease that affects approximately 3% of the world's population. It is characterized by the appearance of red, scaly lesions on different parts of the body, such as elbows, knees and scalp. Although it is not contagious, psoriasis can cause significant impacts on patients' quality of life, including mental health problems such as depression and anxiety. Recent studies have shown a strong association between psoriasis and mental health problems. It is believed that the shame and stigma associated with psoriasis lesions may contribute to the development of these problems. Additionally, psoriasis is a chronic disease that can be difficult to treat, which can increase stress and anxiety in patients. The immune system may also play a role in the relationship between psoriasis and mental health, as the chronic inflammation associated with the disease can affect brain function. Objective: The objective of this systematic review was to analyze scientific studies published in the last 10 years on the relationship between *psoriasis, depression and anxiety in university students. We sought to understand the relevance of this topic and identify the main findings in the literature. Methodology: To carry out this review, we used the Prisma checklist (Preferred Reporting Items for Systematic Reviews and Meta-Analyses). The search was conducted in the PubMed, Scielo and Web of Science databases, considering articles published between 2014 and 2024. The descriptors used were: "psoriasis", "depression", "anxiety", "mental health" and "Quality of life ”. Only articles that addressed the relationship between these constructs in university students were included. Inclusion Criteria: 1. Studies published in the last 10 years. 2. Focus on the relationship between psoriasis, depression and anxiety. 3. Studies with samples of university students. Exclusion Criteria: 1. Articles that did not address the relationship between the constructs. 2. Dissertations, theses and clinical trials.Results: The review identified 15 relevant articles. Psoriasis is associated with an increased risk of depression and anxiety. Psoriasis patients often face emotional challenges such as shame, stigma, and prejudice due to visible skin lesions. The disease can affect patients' self-esteem, quality of life and psychological well-being. Risk Factors and Biological Mechanisms: Chronic inflammation associated with psoriasis can affect brain function and contribute to the development of mental disorders. Emotional stress can trigger and worsen psoriasis symptoms, creating a cycle of negative impact on mental health. Conclusion: This systematic review reinforces the influence of psoriasis on students' lives and its relationship with depression and anxiety. However, there is still a lack of more in-depth studies on this topic. Understanding these disorders is crucial to improving the mental health and socioeconomic well-being of society.