IMPACT OF PSYCHOLOGICAL DISORDERS ASSOCIATED WITH DERMATOLOGICAL DISEASES ON CLINICAL OUTCOMES AND QUALITY OF LIFE

Abstract

The association between dermatological diseases and psychological disorders has increasingly been recognized as a relevant component in the clinical management of these patients. Chronic skin conditions, often visible and stigmatizing, are directly linked to the development of emotional disturbances such as anxiety, depression, and psychosocial distress, significantly impacting quality of life. This study aimed to critically analyze recent literature on the impact of psychological disorders associated with dermatological diseases on clinical outcomes and patients’ quality of life. A systematic review of the literature was conducted using PubMed, SciELO, LILACS, and the Cochrane Libary databases, covering the period from 2020 to 2025. Original studies, systematic reviews and observational studies assessing psychological disorders in patients with dermatological conditions and their relationship with clinical outcomes and quality of life were included. A total of 25 studies met the eligibility criteria and were included in the analysis. The findings demonstrate a consistent association between dermatological diseases and a higher prevalence of psychological disorders, particularly depression and anxiety. Patients with conditions such as psoriasis, atopic dermatitis, acne, and vitiligo exhibited significantly higher levels of emotional distress, negative self-perception, and impairment in social interactions. Furthermore, the presence of psychiatric comorbidities was associated with poorer treatment adherence, increased perception of disease severity, and worse clinical outcomes. Quality of life was substantially reduced across most of the analyzed studies, highlighting the multidimensional burden of these conditions. Despite the consistency of the findings, relevant limitations were identified, including methodological heterogeneity, variability in psychological assessment tools, and differences in study populations. Nevertheless, the evidence reinforces the importance of an integrated approach in the management of dermatological patients, addressing both physical and psychological aspects of the disease.In conclusion, psychological disorders significantly influence clinical outcomes and quality of life in patients with dermatological diseases. The incorporation of psychological assessment and support into dermatological care is essential to improve therapeutic outcomes and overall patient well-being.