SEPSIS PROTOCOL IN THE HOSPITAL SETTING: AN EXPERIENCE REPORT FROM A MEDIUM/HIGH COMPLEXITY HOSPITAL

Abstract

Sepsis is a severe and potentially fatal clinical condition characterized by a dysregulated inflammatory response of the host to infection, leading to organ dysfunction and high mortality rates. It represents a major public health problem, particularly in medium- and high-complexity hospital settings, such as emergency departments and intensive care units. Factors including advanced age, the presence of comorbidities, immunosuppression, and delayed diagnosis are associated with poorer outcomes. Early recognition and prompt initiation of treatment are critical for reducing mortality, making sepsis protocols an essential tool in this context. These protocols emphasize rapid identification of clinical signs, timely collection of essential laboratory tests—particularly serum lactate measurement—early administration of broad-spectrum antibiotics, and adequate fluid resuscitation. Effective implementation requires coordinated and integrated action by a multidisciplinary healthcare team, including physicians, nurses, and pharmacists. This experience report describes the implementation of a sepsis protocol in a medium- to high-complexity hospital, highlighting operational challenges, observed benefits, and the importance of standardized management in optimizing patient care, reducing complications, improving clinical outcomes, and decreasing sepsis-related mortality rates.