A PRESERVAÇÃO DA FERTILIDADE EM MULHERES JOVENS SUBMETIDAS AO TRATAMENTO DE CÂNCER DE MAMA

Natália de Mendonça Lima; Lígia Rosa Farias; Myllela Gonçalves Ferreira; Ana Beatriz de Oliveira Bitarães; Isabella Luques Araújo Teixeira; Juliana Pereira Soares

doi:10.51891/rease.v11i8.20608

Authors

Natália de Mendonça Lima Universidade de Vassouras
Lígia Rosa Farias Universidade de Vassouras
Myllela Gonçalves Ferreira Universidade de Vassouras
Ana Beatriz de Oliveira Bitarães Universidade de Vassouras
Isabella Luques Araújo Teixeira Universidade de Vassouras
Juliana Pereira Soares Universidade de Vassouras

DOI:

https://doi.org/10.51891/rease.v11i8.20608

Keywords:

Breast cancer. Fertility preservation. Treatment.

Abstract

Breast cancer is the most prevalent neoplasm among women in Brazil, after non-melanoma skin cancer, with a higher incidence after the age of 50. However, it also affects women under 40, usually in a more aggressive form and with later diagnosis. The treatment of the disease in younger women raises concerns about fertility, as its gonadotoxic side effects often lead to early menopause. The aim of this study was to analyze the characteristics and benefits of fertility preservation methods in women undergoing breast cancer treatment. A literature review was conducted using the PubMed and Regional Portal of the Virtual Health Library (BVS) databases, and a total of 23 articles were selected after applying inclusion and exclusion criteria. The analyzed studies showed that the use of gonadotropin-releasing hormone (GnRH) analogs and gamete cryopreservation through controlled ovarian stimulation (COS) offer benefits for fertility maintenance in these patients. Nevertheless, COS, considered the gold standard, is still a developing technique. Therefore, further studies are essential to advance this field and improve patient outcomes.