EFFICACY OF LOW-DOSE ASPIRIN IN THE PREVENTION OF HYPERTENSIVE COMPLICATIONS IN PREGNANCY

Authors

DOI:

https://doi.org/10.51891/rease.v11i8.20557

Keywords:

Hypertension. Aspirin. Pregnancy. Pre-eclampsia. Narrative review.

Abstract

Objective: To evaluate the efficacy and safety of low-dose aspirin in preventing complications related to hypertension during pregnancy. Methods: This study is a simple literature review. Articles were selected based on searches in the PubMED database using predetermined keywords and inclusion and exclusion criteria. Results: The analyzed articles presented discrepancies regarding the timing of treatment initiation and the recommended optimal dose. In this context, it is possible to conclude that aspirin in higher doses (≥ 100 mg/day), started before the 16th week of gestation, demonstrates efficacy in preventing preeclampsia. Conclusions: This study reinforces the importance of an individualized approach to the pharmacological prevention of hypertensive complications in pregnancy using low-dose aspirin, given the discrepancies found in the analyzed studies regarding dosage, timing of treatment initiation, and its effects.

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Author Biographies

Ana Carolina Peixoto da Silva, FAMEMA

Graduanda de Medicina, Faculdade de Medicina de Marília - FAMEMA, Marília, SP, Brasil. Orcid ID: 0009-0005-7851-7987.

Diego Pacheco Tavares Veiga, UNCISAL

Graduando de Medicina, Universidade Estadual de Ciências da Saúde de Alagoas - UNCISAL, Maceió,  AL, Brasil. Orcid ID: 0009-0004-1614-9755.

Eduarda Santos Elias das Neves, UNIRIO

Graduanda de Medicina, Universidade Federal do Estado do Rio de Janeiro - UNIRIO, Rio de Janeiro, RJ, Brasil. Orcid ID: 0009-0004-9758-1186.

Mariana Gianisella Ribeiro, UNISA

Graduanda de Medicina, Universidade Santo Amaro - UNISA, São Paulo, SP, Brasil. Orcid ID: 0009-0007-9874-9720.

Rafaela Gazoli Barbosa, UNIMAR

Graduanda de Medicina, Universidade de Marília - UNIMAR, Marília, SP, Brasil. Orcid ID: 0009-0003-7608-9160.

Rafaella Storck Gomes Cavalcante, UNITPAC

Graduanda de Medicina, Centro Universitário Tocantinense Presidente Antônio Carlos UNITPAC, Araguaína, TO, Brasil.Orcid ID: 0009-0009-8649-1237.

Published

2025-08-06

How to Cite

Silva, A. C. P. da, Veiga, D. P. T., Neves, E. S. E. das, Ribeiro, M. G., Barbosa, R. G., & Cavalcante, R. S. G. (2025). EFFICACY OF LOW-DOSE ASPIRIN IN THE PREVENTION OF HYPERTENSIVE COMPLICATIONS IN PREGNANCY. Revista Ibero-Americana De Humanidades, Ciências E Educação, 11(8), 565–574. https://doi.org/10.51891/rease.v11i8.20557