HIGH-GRADE SEROUS CARCINOMA OF THE FALLOPIAN TUBES: CASE REPORT PRESENTATION

Abstract

Introduction: Primary tumors of the fallopian tubes are rare, usually malignant, and difficult to diagnose preoperatively. They are associated with infertility and BRCA1 or BRCA2 gene mutations. Prophylactic salpingo-oophorectomy is currently being discussed due to the high risk of progression to ovarian cancer. Case Report: A 38-year-old woman presented with hypogastric pain, partially relieved with common analgesics. Transvaginal ultrasound revealed a cystic image suggestive of hydrosalpingitis, treated with antibiotics on two occasions. Due to reproductive desire, laparoscopic salpingostomy and chromopertubation were performed, during which a tumor mass with adhesions was identified. A right adnexectomy was carried out. Histopathological analysis confirmed a high-grade serous carcinoma in the right fallopian tube, with metastasis to the ipsilateral ovary and lymphovascular invasion. Abdominal and pelvic CT scans showed local invasion, while cranial and thoracic CTs found no evidence of distant metastases. Conclusion: High-grade serous carcinoma of the fallopian tube is rare and often diagnosed at advanced stages. It should be considered in infertile women or those with BRCA mutations. Awareness of its clinical presentation and appropriate therapeutic approach is essential for early diagnosis and effective management.