THE THERAPEUTIC POTENTIAL OF NATURAL COMPOUNDS IN THE PHARMACOLOGICAL TREATMENT OF ALZHEIMER'S DISEASE: A SYSTEMATIC REVIEW

Authors

DOI:

https://doi.org/10.51891/rease.v11i6.19848

Keywords:

Alzheimer's disease. Donepezil. Phytotherapy.

Abstract

This study aims to investigate different therapeutic approaches for patients suffering from Alzheimer's disease, encompassing both integrative and natural therapies, with the aim of identifying the most effective strategies for improving cognitive function. To achieve this objective, a detailed systematic review was conducted to compile existing research on the subject. Results: One study indicated that the combination of donepezil with choline alfoscerate brought positive results in terms of cognitive improvement. In contrast, alternatives such as ginkgo biloba and acetyl-L-carnitine did not provide beneficial benefits. On the other hand, approaches using formulas from traditional Chinese medicine, such as KGT, showed therapeutic potential, although further studies are needed to validate their efficacy and safety over time. Conclusion: The integration of conventional treatments with natural therapies, always under the supervision of a health professional, may represent a promising alternative in the fight against Alzheimer's disease.

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Author Biographies

Nivia Colares Couto, Centro Universitário da Amazônia

Farmacêutica. Orientadora. Centro Universitário da Amazônia. 

José Nazareno, IFPEC

Pós-graduando em Farmácia Clínica e Hospitalar. Instituto de Formação Profissional e Educação Continuada (IFPEC). 

Thiago Colares Freitas, Centro Universitário da Amazônia

Graduando em Farmácia. Centro Universitário da Amazônia. 

 

Published

2025-06-10

How to Cite

Couto, N. C., Freitas, J. N. da S., & Freitas, T. C. (2025). THE THERAPEUTIC POTENTIAL OF NATURAL COMPOUNDS IN THE PHARMACOLOGICAL TREATMENT OF ALZHEIMER’S DISEASE: A SYSTEMATIC REVIEW. Revista Ibero-Americana De Humanidades, Ciências E Educação, 11(6), 2007–2018. https://doi.org/10.51891/rease.v11i6.19848