LABORATORY TESTS IN AESTHETICS: EVALUATION OF MICROBIOTA AND DERMATOLOGICAL IMPACTS

Abstract

Aesthetic Biomedicine has emerged as a field focused on promoting health, beauty, and well-being, emphasizing the safety and effectiveness of procedures. Laboratory testing, as outlined by Resolution No. 347/2022, is essential for identifying systemic dysfunctions that may interfere with aesthetic outcomes. Among these, intestinal dysbiosis has gained attention due to its influence on skin health. Alterations in gut microbiota composition can trigger low-grade systemic inflammation, disrupting skin homeostasis through the gut-skin axis. Scientific evidence shows a strong association between dysbiosis and dermatological conditions such as acne, melasma, and premature aging. In this context, laboratory assessments—such as fecal microbiome genetic sequencing, hydrogen breath tests, and inflammatory markers like C-reactive protein and interleukins—are essential for personalized aesthetic approaches. This study, through a qualitative literature review of publications from 2015 to 2025, analyzes the relationship between gut microbiota and aesthetic dysfunctions, highlighting the importance of laboratory diagnostics in aesthetic biomedicine and the therapeutic potential of modulatory strategies such as probiotics and prebiotics.