NON-INSTRUMENTAL ENDODONTIC THERAPEUTIC APPROACH (TENI) IN PRIMARY TEETH USING CTZ PASTE: A LITERATURE REVIEW

Abstract

Introduction: The deciduous dentition is essential for masticatory, phonetic and aesthetic functions, in addition to preserving space for the permanent teeth that will erupt. Early childhood caries is a public health problem, which can lead to early tooth loss and impact child development. Conventional endodontic treatment in children presents challenges, such as anatomical complexity and management of child behavior. In this context, Non-Instrumental Endodontic Therapy (NIENT) emerges as a minimally invasive alternative, reducing clinical time. CTZ paste, composed of chloramphenicol, tetracycline and zinc oxide-eugenol, has stood out as an effective option for controlling endodontic infection in deciduous teeth, promoting decontamination of the canals and maintenance of the dentition until its natural exfoliation. Objective: This study aims to review the literature on the efficacy of the TENI approach associated with the use of CTZ paste in the endodontic treatment of primary dentition, evaluating its benefits, limitations, and clinical prognosis. Materials and Methods: This is a literature review based on the search and analysis of scientific articles published in electronic databases such as PubMed, NIH, Europe PMC, Scielo, and LILACS. The search was limited to 8 articles published between 2018 and 2025, including publications in Portuguese, English, and Spanish. Results: CTZ paste proved to be effective and safe in the treatment of primary teeth with pulp necrosis using the TENI technique, demonstrating biocompatibility with periapical tissues and clinical and radiographic results comparable to or superior to traditional methods, with the advantage of shorter clinical time and cost. Conclusion: CTZ paste is a promising alternative for endodontic treatment of primary teeth, with good clinical results, lower cost, and clinical time. Further studies are needed.