PEMPHIGUS FOLIACEUS IN A DOG: CASE REPORT

Abstract

Pemphigus foliaceus is an autoimmune dermatopathy that affects the epidermis, characterized by the formation of pustules, crusts and scaling, especially in areas such as the face. The condition results from an immunological response against desmosomes, structures essential for adhesion between skin cells. Early diagnosis is crucial for effective management of the disease, as it reduces complications and improves the animal's quality of life. This case report describes a dog that presented skin lesions initially manifested as superficial pustules, progressing to erosions and crusts located on the face and ears, later spreading to the abdominal and thoracic regions. Skin cytology revealed acantholytic cells, suggesting an autoimmune disease, later confirmed by histopathological examination. Therapeutic follow-up showed a positive clinical response, with a significant reduction in skin lesions. This report highlights the importance of early diagnosis and continuous management in controlling pemphigus foliaceus, highlighting the need for frequent clinical monitoring for therapeutic adjustments. This monitoring aims to provide the animal with well-being, minimize the risk of adverse effects, optimize the response to treatment and reduce possible complications.