AVANÇOS NO TRATAMENTO DA DOENÇA DE CROHN: UMA ABORDAGEM INTEGRADA E PERSONALIZADA

Luísa Miranda Braga Lopes; Camila Trotta Lourenço de Lemos; Luiza Rezende Manna; Maria Eduarda Marini Amante Gomide; Norival Garcia da Silva Neto; Milena Silva e Sousa; Ulisses Gonçalves Teixeira; Bruno Arêas Reis de Almeida; Adriana Rodrigues Ferraz

doi:10.51891/rease.v10i10.15868

Authors

Luísa Miranda Braga Lopes Universidade de Vassouras
Camila Trotta Lourenço de Lemos Universidade de Vassouras
Luiza Rezende Manna Universidade de Vassouras
Maria Eduarda Marini Amante Gomide Universidade de Vassouras
Norival Garcia da Silva Neto Universidade de Vassouras
Milena Silva e Sousa Universidade de Vassouras
Ulisses Gonçalves Teixeira Universidade de Vassouras
Bruno Arêas Reis de Almeida Universidade de Vassouras
Adriana Rodrigues Ferraz Universidade de Vassouras

DOI:

https://doi.org/10.51891/rease.v10i10.15868

Keywords:

Crohn. Inflammation. treatment.

Abstract

Crohn's Disease (CD) is a chronic inflammatory bowel condition affecting the gastrointestinal tract. The treatment of CD has evolved with the introduction of biological therapies, such as TNF-alpha inhibitors, which provide remission and improve patients' quality of life. Alternatives like vedolizumab, ustekinumab, and tofacitinib have emerged for those who do not adequately respond to conventional therapies. Surgery remains crucial in cases of complications, and the combination of pharmacological and surgical interventions has shown significant benefits. Dietary approaches and lifestyle changes are also important for disease management. The cost-effectiveness analysis of therapies is essential to ensure access to effective treatments. The future of CD management lies in the personalization of treatment, considering individual patient characteristics and their responses to different interventions.