PROFILE OF CHANGES IN THE BLOOD CELLS OF PATIENTS INFECTED BY COVID-19

Abstract

The SARS-CoV-2 virus is responsible for Covid-19. This virus binds to cellular components present in the host's cells and takes advantage of its cellular machinery to produce new viruses. The viral infection produces an inflammatory response, which can develop serious damage to the cardiovascular and respiratory systems, as well as a systemic inflammatory response. The beginning and evolution of cellular damage can be seen through hematological findings, mainly in the count of neutrophils and lymphocytes, in infected patients. This is an integrative review of the literature on the profile of changes in the blood cells of patients infected by Covid-19. 17 articles were found in the literature, which meet the inclusion and exclusion criteria. The pharmacist who works in the clinical laboratory (hematology sector) is responsible for managing it, through the analysis and interpretation of data, which will assist the doctor. Therefore, there is a lack of more studies that show the flow of quality management in the clinical laboratory, from its pre-analysis, analysis and post-analysis, which emphasizes the presence of the pharmacist and the sharing of information with the healthcare team, in this essential service to the population, during the pandemic.