HEPATIC LIPIDOSIS IN FELINES

Abstract

 Hepatic Lipidosis (HL) is a disease reported in adult cats, defined by an accumulation of fat in hepatocytes, impairing liver metabolism. It can progress rapidly and become liver failure, which is fatal if not treated early. The most frequent clinical signs include anorexia, weight loss, jaundice, apathy, and lethargy. Diagnosis is made by associating clinical findings, laboratory tests, imaging studies, and histopathological evaluation of the liver. The triggering factors for HL are multifactorial, including catabolic states such as prolonged anorexia, diabetes mellitus, pancreatitis, and other metabolic conditions. Treatment mainly consists of intensive nutritional support, electrolyte correction, and management of underlying diseases. This study reviews national and international scientific data published between 2000 and 2025, aiming to deepen the understanding of the etiology, pathophysiology, diagnosis, and treatment of hepatic lipidosis in felines.