ADVANCES IN BIOLOGICAL THERAPIES FOR NEUROSURGICAL ANESTHESIA: A NARRATIVE REVIEW OF MONOCLONAL ANTIBODIES AND GENE THERAPY APPLICATIONS IN BRAIN TUMOR MANAGEMENT AND NEURODEGENERATIVE DISEASES

Autores

  • Giulia Canello Machado PUCRS
  • Beatriz Viana Souto da Silva Centro Universitário Christus
  • Elena Antunes de Vasconcelos EBMSP
  • Afrânio Côgo Destefani EMESCAM
  • Vinícius Côgo Destefani DynMolLab

DOI:

https://doi.org/10.51891/rease.v10i8.15321

Palavras-chave:

Monoclonal Antibodies. Gene Therapy. Neurosurgical Procedures. Brain Neoplasms. Neurodegenerative Diseases.

Resumo

Neurosurgical anesthesia has seen significant progress with the introduction of biological therapies, particularly monoclonal antibodies and gene therapy. These novel treatments hold immense potential in the management of complex neurological conditions, notably brain tumors and neurodegenerative diseases. The promise of monoclonal antibodies that target specific antigens as adjuvant therapies for aggressive malignancies like glioblastoma, and gene therapy's objective to correct genetic abnormalities responsible for various neurological disorders, are particularly noteworthy. This narrative review aims to provide a comprehensive overview of the current research, challenges, and future directions of these biological therapies in the context of neurosurgical anesthesia.

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Biografia do Autor

  • Giulia Canello Machado, PUCRS

    PUCRS. 

  • Beatriz Viana Souto da Silva, Centro Universitário Christus

    Centro Universitário Christus (Unichristus). 

  • Elena Antunes de Vasconcelos, EBMSP

    Escola Bahiana de Medicina e Saúde Pública - EBMSP.

  • Afrânio Côgo Destefani, EMESCAM

    Santa Casa de Misericórdia de Vitoria Higher School of Sciences - EMESCAM. Santa Luíza – Vitória – ES Brazil Molecular Dynamics and Modeling Laboratory (DynMolLab), 

  • Vinícius Côgo Destefani, DynMolLab

    Molecular Dynamics and Modeling Laboratory (DynMolLab), Santa Luíza – Vitória – ES – Brazil.

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Publicado

2024-08-21

Edição

v. 10 n. 8 (2024): Revista Ibero-Americana de Humanidades, Ciências e Educação — REASE

Seção

Artigos

Categorias

Licença

Atribuição CC BY

 

Como Citar

Machado, G. C., Silva, B. V. S. da, Vasconcelos, E. A. de, Destefani, A. C., & Destefani, V. C. (2024). ADVANCES IN BIOLOGICAL THERAPIES FOR NEUROSURGICAL ANESTHESIA: A NARRATIVE REVIEW OF MONOCLONAL ANTIBODIES AND GENE THERAPY APPLICATIONS IN BRAIN TUMOR MANAGEMENT AND NEURODEGENERATIVE DISEASES. Revista Ibero-Americana de Humanidades, Ciências e Educação, 10(8), 2517-2523. https://doi.org/10.51891/rease.v10i8.15321

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