IMPACTS GENERATED BY THE USE OF CHLOROQUINE, HYDROXYCHLOROQUINE AND AZITHROMYCIN AS TREATMENT OF PATIENTS WITH COVID-19

Abstract

Due to the seriousness of the world scenario devastated by the coronavirus pandemic, drug testing was started in order to find a more effective and safe solution for the treatment of COVID-19. In preliminary studies, drugs such as chloroquine and hydroxychloroquine associated with azithromycin had antiviral activity against SARS-CoV-2. Given the above, this study aimed to evaluate the impacts of the use of chloroquine, hydroxychloroquine and azithromycin in the treatment of patients with COVID-19. For this, a systematic literature review of a descriptive nature was carried out in several databases, with the time interval between 2019 and 2021, using the descriptors in health sciences (DeCS): Covid-19, Sars-CoV-2, Hydroxychloroquine, Chloroquine and Azithromycin, using the Boolean operator "AND". After analyzing the articles, it was found that chloroquine, hydroxychloroquine and azithromycin did not bear efficiency in the treatment of COVID-19 and that the patients' heart rhythm was compromised as a result of the effects existing during the treatment.