DEVELOPMENT OF NEW NEUROPROTECTIVE THERAPIES FOR GLAUCOMA
DOI:
https://doi.org/10.51891/rease.v11i6.19232Keywords:
Glaucoma. Neuroprotective therapies. Retinal ganglion cells (RGCs). Oxidative stress.Abstract
Glaucoma is a chronic optic neuropathy characterized by progressive degeneration of the optic nerve, often associated with elevated intraocular pressure (IOP). Traditional therapies focus on reducing IOP but fail to directly address neuronal damage. This study aims to explore the development of new neuroprotective approaches for the treatment of glaucoma. The research, of a bibliographic nature, reviews recent studies on neuronal protection mechanisms, including the use of antioxidants, glutamate inhibitors and gene therapy. New therapies aim not only to slow the progression of the disease, but also to preserve the patient's visual functionality. The results indicate that biotechnology-based neuroprotective strategies can complement conventional treatments and improve the quality of life of patients. The relevance of this study lies in its contribution to the advancement of ophthalmology, indicating new directions for the clinical management of glaucoma.
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Atribuição CC BY