SICKLE CELL ANEMIA: MANIFESTATIONS CLINICS AND DIAGNOSIS LABORATORIES

Abstract

Sickle cell anemia is a genetic disease that causes anemia and other health problems. Clinical manifestations include severe pain, fatigue, jaundice and vaso-occlusion attacks. Laboratory diagnosis involves blood tests, such as hemoglobin electrophoresis, to identify the presence of hemoglobin, a characteristic of the disease. Treatment aims to alleviate symptoms and prevent complications, with blood transfusions, medications and, in some cases, cell transplants. Method: literature review, consultations in books, dissertations and scientific articles. Results: The diagnosis of hemoglobinopathies is complex and involves an analysis that must consider clinical data, genetic inheritance, age, sex, among other factors. Conclusion: the pathophysiological changes of sickle cell anemia can sometimes seriously interfere in the daily lives of individuals with it, understanding that early identification is essential, bringing an improvement in the quality of life of patients.