USE OF BIOMARKERS IN EARLY DIAGNOSIS OF BREAST CANCER: AN INTEGRATIVE REVIEW

Abstract

Breast cancer is a leading cause of mortality among women, and early detection is crucial to improving clinical outcomes. The use of biomarkers has emerged as a promising approach for early identification of the disease, providing an opportunity for more effective and personalized interventions. This integrative review examines the efficacy and applicability of several biomarkers in the early diagnosis of breast cancer. Through the analysis of recent studies, biomarkers that show significant potential in early detection were identified, including circulating proteins, microRNAs and tumor DNA fragments. The review also discusses the methodologies used to detect these biomarkers, the accuracy of the tests and their clinical implications. Evidence suggests that the integration of these biomarkers into clinical practices can significantly improve the ability to diagnose breast cancer at an early stage, offering promising prospects for improving survival and quality of life of patients.