IMPORTANCE OF MAGNESIUM SULFATE FOR FETAL NEUROPROTECTION IN PREGNANCY BELOW 32 WEEKS

Abstract

Objective: To demonstrate the importance and viability of magnesium sulfate for fetal neuroprotection in premature pregnancies, especially those less than 32 weeks. Methodology: This is a systematic review, with a qualitative approach, of the current literature from the scientific databases MEDLINE, EMBASE and Virtual Health Library, carried out in August 2024, through a targeted search process through combinations of DeCS/MeSH descriptors using the operator “and” between the terms, as represented: "Magnesium Sulfate" and "Pregnancy" and "Neuroprotection" and "Sulfato de Magnésio" and "Gravidez" and "Neuroproteção". Results and Discussion: After carrying out the process aimed at searching for studies to be included, according to the chosen scientific databases, 13 studies were listed to participate in the theoretical basis of this article. These were selected according to exclusion and inclusion criteria, as well as through search filters, in addition to subsequently undergoing a stage of data analysis and systematization, in order to define the importance of magnesium sulfate for fetal neuroprotection in pregnancies of less than 32 weeks. Final Considerations: The use of magnesium sulfate in preterm pregnancies of less than 32 weeks showed a reduction in the risk of moderate to severe cerebral palsy in survivors.