PEDIATRIC MULTISSYSTEM INFLAMMATORY SYNDROME(SIM-P) ASSOCIATED WITH COVID-19: A REVIEW OF THE LITERATURE OF TREATMENT WITH INTRAVENOUS IMMUNOGLOBULIN INFUSION

Abstract

SARS-CoV-2 infection is typically very mild and often asymptomatic in children. One complication is the rare multisystem inflammatory syndrome in children (MIS-C) associated with COVID-19, presenting 4 to 6 weeks after infection as high fever, organ dysfunction, and sharply elevated markers of inflammation. The pathogenesis is unclear, but it has overlapping features with Kawasaki disease suggestive of vasculitis and a probable autoimmune etiology, with timely treatment being a preponderant factor in altering the course of the disease and subsequent complications.