USE OF PIPER METHYSTICUM (L.) AND PASSIFLORA INCARNATA (L.) IN THE TREATMENT OF GENERALIZED ANXIETY DISORDER

Abstract

: The control measures recommended in the context of the COVID-19 pandemic have affected the population in many calibers of living and health conditions, and among them significantly the mental health component such as anxiety and depression. Objective: To review, through scientific literature, the efficacy, pharmacological interactions and benefits of using the herbal medicines kava-kava (Piper methysticum L.) and passion fruit (Passiflora incarnata L.) as therapeutic alternatives for the treatment of Generalized Anxiety Disorder (GAD), aggravated in times of pandemic. Methods: This is a qualitative systematic literature review, which used the electronic sites SciELO, PubMed, Google Scholar, NHSA and WHO to search for data. Results: It was observed that the main benefits of the use of herbal medicines are the reduced cost, easy access, and low rate of side effects and adverse reactions. A considerable number of information was found that demonstrated the use and demand for P. Incarnata-based herbal medicines to treat psychopathologies such as GAD, during social isolation and quarantine. No significant numbers of studies were found that could prove the use of P. Methysticum during the COVID-19 pandemic. Final remarks: It is suggested that P. Incarnata and P. Methysticum species are effective for the treatment of GAD by having high medicinal value with anxiolytic, anticonvulsant and sedative pharmacological properties.