RESISTANT ARTERIAL HYPERTENSION DUE TO PRIMARY HYPERALDOSTERONISM: A LITERATURE REVIEW

Abstract

Resistant arterial hypertension (RAH) occurs when elevated blood pressure persists despite lifestyle modifications and the use of three different classes of antihypertensive medications. One of its causes may stem from primary hyperaldosteronism (PHA), characterized by inappropriately elevated aldosterone production independent of the renin-angiotensin system. This leads to cardiovascular damage, hypertension, and electrolyte imbalances. Once properly identified, this comorbidity has the potential for treatment and cure, with these measures playing a crucial role in reducing complications associated with hypertension. Accurate diagnosis is essential for specific therapeutic interventions, improving not only blood pressure control but also adverse cardiovascular outcomes.