SKELETAL MUSCLE AS AN ENDOCRINE ORGAN: PHYSIOLOGICAL REPERCUSSIONS ON THE HEALTH OF THE ELDERLY

Abstract

Aging is associated with physiological changes, including a decline in skeletal muscle mass, strength, and function, which can compromise the quality of life of older adults. Muscle tissue is currently recognized not only for its mechanical functions but also for its metabolic and endocrine activity, particularly through the production and release of myokines that facilitate communication between muscle and various tissues and organs. In this context, this study aimed to analyze skeletal muscle as an endocrine organ and its physiological implications for the health of older adults. This literature review was based on an analysis of scientific studies regarding the endocrine function of skeletal muscle, the role of myokines, and age-related muscle changes. The findings indicate that myokines participate in physiological processes, including the regulation of energy metabolism, insulin sensitivity, inflammatory responses, and inter-system communication. Consequently, the decline in muscle mass and activity during aging can negatively impact the body's homeostasis. The study concludes that skeletal muscle performs an endocrine function and that its preservation is crucial for maintaining the health and functional capacity of older adults.