PLATELET COUNTS AND COAGULATION TESTS BEFORE INJECTABLE AESTHETIC PROCEDURES: A NARRATIVE REVIEW

Abstract

This review aimed to analyze the evidence on platelet counts and coagulation tests before injectable aesthetic procedures. A descriptive, qualitative narrative review was conducted, with an initial search in five databases and a supplementary PubMed/MEDLINE search in August 2026. Twenty-seven studies published between 2016 and 2026 were included and organized into seven thematic areas, without a formal risk-of-bias assessment. Studies on injectable procedures described bleeding complications, technical factors, and preventive measures but did not compare laboratory testing strategies. Indirect evidence, mainly from surgical and outpatient settings, favored individualized assessment guided by bleeding history, comorbidities, medications, and procedural risk. Platelet counts and coagulation tests served complementary purposes and did not replace clinical assessment. In platelet-rich plasma studies, counts characterized the concentrate or investigated its efficacy, without demonstrating an ability to predict bleeding. The selected studies do not support universal testing, nor do they justify omitting testing in all patients. Selective testing is supported by indirect evidence, but its specific benefit remains uncertain. Heterogeneity and the absence of direct comparisons limit the establishment of protocols and laboratory cutoffs.