MULTICENTRIC LYMPHOMA IN A DOG: CASE REPORT

Abstract

Lymphoma is a neoplasm characterized by the proliferation of malignant lymphoid cells, this neoplasm mainly affects lymphoid tissues such as the spleen and bone marrow, but can develop in any organ, such as the liver. Its cause is not well understood, but multifactorial etiology, genetic factors, immune deficiency and chemical carcinogens are believed. The classification is based on its anatomical, histological and immunophenotypic characteristics, there are four anatomical classifications for lymphoma: multicentric, food or digestive, mediastinal and extranodal, and 80% of cases in dogs are classified as multicentric lymphomas. The clinical signs of this disease vary from its location and tumor extension. The diagnosis begins with a physical examination and complementary tests such as blood count, biochemical profile, and imaging tests such as abdominal ultrasound, but in order to obtain a definitive diagnosis, cytological, histopathological and immunohistochemical analysis is necessary, which will help in establishing the diagnosis. animal prognosis. The treatment is defined based on the histological type, clinical stage, extension and severity of the case and the prognosis is also particular to each case. The reported patient of the Labrador breed, 11 years old, was diagnosed with splenic lymphoma and underwent splenectomy as a therapeutic treatment.