TOXINA BOTULÍNICA APLICADA PARA FINS TERAPÊUTICOS

Abstract

Clostridium botulinum is a strictly anaerobic, spore-forming gram-positive organism, producing a potent neurotoxin called Botulinum Toxin Type A (TBA), which is effective for patients during treatment and procedures. Quality of life plays an extremely effective role and is one of the most used non-surgical methods in Brazil. Injecting intramuscularly where you want results, TBA binds to terminal

receptors on motor nerves, inhibits the release of acetylcholine, and ultimately prevents muscle contraction, resulting in temporary muscle relaxation. Therefore, it was used clinically by Allan Scott, an ophthalmologist from California (USA), to correct strabismus in the 1980s. Then, involuntary movements such as blepharospasm and hemifacial spasm occurred, making it the first choice for the treatment of these diseases. It was later used for cervical dystonia, spastic dystonia, focal hand and leg dystonia, specific motor dystonia, and tremor. In recent years, the scope of indications for botulinum toxin treatment has increased significantly and is now used to treat spasms, rehabilitation programs, bladder or anal sphincter dysfunction, tension headaches and even as a cosmetic treatment to eliminate wrinkles. facials. Botulinum toxin type A is also used as a treatment for chronic migraine and hyperhidrosis and is an alternative treatment option to surgery for certain pathological conditions.