VON WILLEBRAND DISEASE: CHALLENGES AND IMPACTS ON WOMEN'S REPRODUCTIVE HEALTH

Abstract

The disease of von Willebrand (DvW) is characterized as a hereditary hemorrhagic disorder, marked by the deficiency or dysfunction of von Willebrand factor, which is essential in coagulation. This condition presents significant challenges in women’s reproductive health, affecting everything from menstruation to pregnancy. Women with DvW frequently experience menorrhagia, which can impact their quality of life and result in anemia. During pregnancy, management becomes even more critical, as hemostatic changes can increase the risk of bleeding and obstetric complications. Studies demonstrate that adequate follow-up and personalized interventions are essential to minimize these risks. Furthermore, gynecological procedures in patients with this condition require special care to prevent excessive bleeding. Early recognition of the condition, combined with a multidisciplinary approach, is essential to ensure the well-being of these women. This review article aims to consolidate current evidence on the challenges and impacts of DvW on reproductive health, exploring its clinical implications and highlighting the importance of appropriate management strategies. Understanding these issues is vital to enhance the care provided to affected women and promote a more integrated and sensitive approach to their reproductive needs.