GUT MICROBIOTA AND DIGESTIVE DISEASES: EXPLORING THE CONNECTIONS TO IMPROVE DIGESTIVE HEALTH

Abstract

The relationship between the intestinal microbiota and digestive diseases has been the subject of increasing interest in medical research. This study addresses the complex interplay between the gut microbiota and digestive health, exploring the connections between microbial composition, gut function and the development of digestive diseases. Through a comprehensive review of the scientific literature, key findings related to the influence of gut microbiota on the pathophysiology of digestive diseases, including irritable bowel syndrome, inflammatory bowel disease, non-alcoholic fatty liver disease, and colorectal cancer, were identified. Furthermore, current and emerging therapeutic strategies aimed at modulating the intestinal microbiota to improve digestive health were discussed. These strategies include the use of probiotics, prebiotics, diet and fecal transplantation, with an emphasis on personalizing treatment according to the individual microbial composition and clinical characteristics of the patient. Finally, knowledge gaps and areas for future research are highlighted, emphasizing the importance of interdisciplinary collaboration to advance our understanding of the gut microbiota and its role in digestive health. This study provides a comprehensive overview of the current state of research and highlights opportunities to improve the management and treatment of digestive diseases through manipulation of the gut microbiota.