STUDY OF THE EFFECTIVENESS OF SACCHAROMYCES CEREVISIAE IN DIARRHEA INDUCED BY SALMONELLA TYPHIMURIUM IN BEAGLE DOGS

Abstract

Gastrointestinal discomforts are one of the main health problems that affect animals in general. Among these infections, canine parvovirus has a higher prevalence of death in puppies younger than 6 months of age. The focus of treatment is initially on measures to control clinical signs, as well as medication, from the use of antiemetics and antibiotics, however resistance to antimicrobials has been one of the main problems faced by control measures, usually related to the use indiscriminate, which in many cases can progress to more serious conditions of the disease. The use of probiotics (live microorganisms), which has been an alternative used, has shown promising results. Among these, Saccharomyces cerevisiae, popularly known as "brewer's yeast", has been used as a probiotic supplement used to prevent or treat diarrheal cases. Given the above, the present study investigated the clinical efficacy of the test product Diarril^®, based on Saccharomyces cerevisiae, in cases of diarrhea artificially induced by Salmonella typhimurium in puppies. Twenty-two Beagle dogs, male and female, puppies, aged between 4 and 8 months, were divided into 3 experimental groups. The dogs were evaluated through physical and laboratory examinations throughout the trial, from the pre-test period (day -7) until the last day of evaluations, which varied according to each animal. From the data obtained, it was verified that the product under test Diarril^® is effective against cases of diarrhea artificially induced by Salmonella typhimurium in puppies, when administered orally, during 10 consecutive days, at a dose of 01 (one) vial of 5 mL containing 50 million Saccharomyces cerevisiae per animal, the administration being divided into two periods, morning and afternoon, according to label and leaflet recommendations.