REGENERATIVE POTENTIAL OF A-PRF IN MAXILLARY SINUS AUGMENTATION ASSOCIATED WITH DENTAL IMPLANTS

Abstract

Maxillary sinus floor elevation is an option for dental implant rehabilitation in patients with reduced bone availability in the posterior maxilla. In this context, advanced platelet-rich fibrin (A-PRF) has attracted interest due to its regenerative potential and autologous origin. The aim of this study was to analyze the available evidence regarding the use of A-PRF in maxillary sinus floor elevation procedures combined with dental implant placement. A literature review was conducted using the PubMed/MEDLINE, Scopus, Web of Science, and SciELO databases, covering clinical and experimental studies, case reports, systematic reviews, and meta-analyses. The analyzed studies demonstrated favorable results regarding bone regeneration, new bone tissue formation, and the feasibility of simultaneous implant placement in selected cases. PRF also showed potential either as a standalone material or in combination with conventional biomaterials. However, the heterogeneity of protocols and assessment methods limits comparisons between studies. It is concluded that A-PRF holds promise as an autologous biomaterial, although standardized clinical studies are required to confirm its efficacy and predictability.