EPIDEMIOLOGICAL PROFILE ASSOCIATED WITH HIV CO-INFECTIONS IN A REFERENCE CENTER IN MARANHÃO, BRAZIL

Abstract

Objective: to characterize the epidemiological profile of HIV co-infected individuals at a Counseling and Testing Center for Sexually Transmitted Infections and AIDS, their clinical status, and associated prognoses. Methods: retrospective, cross-sectional, quantitative study, with descriptive and analytical approach; the sociodemographic, epidemiological, clinical and pharmacotherapeutic variables were obtained from medical records, outpatient records and results of confirmatory tests, from January 2015 to December 2020, arranged in a structured collection instrument. They were analyzed using the Statistical Package for the Social Sciences (SPSS), using Pearson's chi-square test, the significance level established was 5% (p<0.05), and the confidence level adopted was 95%. Results: 104 medical records were analyzed, which predominantly were male (64.4%), brown, and were between 21 and 40 years of age; the co-infections present were syphilis (55.8%), tuberculosis (19.2%), toxoplasmosis (12.5%), herpes zoster (9.6%), leishmaniasis (8.7%) and hepatitis B (3.8%); 42.3% of the patients analyzed had the AIDS form of the disease; there was a significant association between regular use of antiretroviral therapy (ART) and the presence of the AIDS form of the disease (p=0.041); male gender was significantly associated with drug use (p=0.020); Low values of CD4+ T lymphocytes were associated with the co-infections leishmaniasis (p=0.014) and hepatitis B (p=0.017); the correlation between co-infection with HIV and syphilis and the non-evolution of these patients to the AIDS form of the disease was visualized (p=0.003). Conclusion: this study predominantly found the presence of the following HIV co-infections: syphilis, tuberculosis, and toxoplasmosis; in male patients in an economically active age group, and a high prevalence of the AIDS form of the disease.