CLINICAL AND RADIOLOGICAL PREDICTORS OF SUCCESSFUL CEREBRAL REPERFUSION AFTER MECHANICAL THROMBECTOMY IN ACUTE ISCHEMIC STROKE

Abstract

This article aimed to analyze the main clinical and radiological predictors associated with the success of cerebral reperfusion after mechanical thrombectomy in patients with acute ischemic stroke, considering the relevance of these factors in therapeutic selection and functional outcomes. This is an integrative literature review, descriptive in nature and with a qualitative approach, carried out through searches in the PubMed/MEDLINE, Virtual Health Library and PubMed Central databases, including studies published between 2015 and 2026, in English, Portuguese and Spanish. Studies involving adult patients undergoing mechanical thrombectomy and investigating clinical, radiological or procedural variables associated with successful cerebral reperfusion, generally defined by modified Thrombolysis in Cerebral Infarction (mTICI) scores ≥2b, were selected. The results showed an association between reperfusion success and factors such as initial neurological severity, time to reperfusion, ASPECTS score, collateral circulation, extent of the ischemic core, thrombus characteristics, and occurrence of the first-pass effect. It is concluded that the integration of clinical variables, advanced neuroimaging, and procedural factors can contribute to greater accuracy in patient selection and optimization of outcomes after mechanical thrombectomy in acute ischemic stroke.