SURGICAL EXCISION ASSOCIATED WITH ELECTROCHEMOTHERAPY IN THE TREATMENT OF FIBROSARCOMA IN A FELINE - CASE REPORT

Abstract

Skin and soft tissue tumors encompass a variety of neoplasms, among which mesenchymal tumors, such as fibrosarcoma, are particularly prevalent in cats. The treatment of choice for fibrosarcoma is surgical excision with wide margins, often complemented by adjuvant therapies. Electrochemotherapy has emerged as an effective therapeutic option, combining the local or systemic administration of low-permeability drugs, such as bleomycin or cisplatin, with the application of localized electric pulses. This technique has gained prominence in veterinary medicine due to its ease of application and low toxicity, becoming one of the first-line treatment options, especially for tumors located in anatomically complex areas where surgical excision can be challenging.The aim of this study is to report a case of multimodal treatment involving excisional biopsy combined with intraoperative electrochemotherapy as a therapeutic approach for fibrosarcoma in a feline patient. Based on the study, it can be concluded that this therapeutic combination was effective in achieving tumor-free surgical margins. The reported case demonstrates how integrating different therapeutic approaches can improve the prognosis of patients with recurrent tumors, highlighting the growing role of electrochemotherapy in veterinary oncology.