CLINICAL PROTOCOLS FOR THE MANAGEMENT AND PREVENTION OF PERIPHERAL NEUROPATHY FOLLOWING CHEMOTHERAPY: A SCOPING REVIEW

Abstract

Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) is an adverse reaction resulting from the neurotoxicity of antineoplastic agents, which compromises functionality and quality of life. Objective: To synthesize evidence regarding instruments and protocols used in the prevention, assessment, and management of CIPN. Method: A scoping review was conducted in accordance with the Joanna Briggs Institute framework and the PRISMA-ScR guidelines, utilizing the PCC (Population, Concept, Context) strategy. Searches were performed in the MEDLINE, LILACS, Web of Science, and Scopus databases, as well as in grey literature; nine studies were included. Results: Instruments based on both professional assessment and self-reporting were identified, including the TNSr, TNSc, EORTC QLQ-CIPN20, FACT/GOG-Ntx, PNQ, PRO-CTCAE, and CIPNAT. Pharmacological and non-pharmacological strategies—such as photobiomodulation—were described, with a particular emphasis on the role of nursing in patient monitoring and health education. Conclusion: CIPN compromises autonomy and well-being. Despite the availability of validated instruments, limitations persist regarding the time required for administration, the need for professional training, and the underestimation of symptoms in clinical practice.